Macrophage electrophoretic mobility (MEM) with myelin basic protein
نویسندگان
چکیده
منابع مشابه
Evaluation of macrophage electrophoretic mobility (MEM) test as an indicator of cellular immunity in ocular tumours.
The macrophage electrophoretic mobility (MEM) test of Field and Caspary did not clearly separate patients with ocular neoplastic disease from those with inflammatory disease, although there was some indication of discrimination between choroidal melanoma and ocular inflammation. In our hands the test failed to give a reproducible result for the immunodiagnosis of ocular malignancy. The techniqu...
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The results of an assessment of the macrophage electrophoretic mobility test in cancer diagnosis are described. We found that the test did not reliably distinguish between a group of 18 patients with benign disorders and a group of 25 with malignant disease.
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Lymphocytes obtained from the blood of patients suffering from malignant disease liberate, when incubated with a basic protein obtained from carci nomatous tissue or the brain, a substance ( slowing factor ) which reduces the electrophoretic mobility of guinea pig macrophages. Lymphocytes from normal subjects or patients with non malignant tumors do not liberate this slowing factor. The macrop...
متن کاملSerum and Saliva Myelin Basic Protein as Multiple Sclerosis Biomarker
Objective: Multiple sclerosis (MS) is presented with motor and sensory function loss. It is caused by demyelination and following axonal lesion. As myelin basic protein (MBP) is one of the key elements of the myelin cover, we examined the level of MBP in serum, stimulated, and unstimulated saliva as a suitable biomarker for detecting MS. Methods: A case-control study was performed in 29 health...
متن کاملMyelin basic protein.
The fact that central nerve tissue is encephalitogenic has been known since the observation of a post-injection reaction of some rabies victims to the Pasteur vaccine that contained nerve tissue (Brostoff, 1977). Subsequently the encephalitogenic agent in central nerve tissue was traced to a component of the myelin sheath, and a protein was finally isolated that in the presence of complete Freu...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1976
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1976.221